By Levels, Committee On Acute Exposure Guideline
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Cognitive function was assessed by the performance index, which was based on serial performance scores in numerical facility and speed of closure tests. Physiologic effects were assessed by blood pressure and heart rate measurements. 0 (mild): subjects show peak heart rate of 80-85 beats/min, systolic blood pressure elevation <10 mm Hg, moderate pupillary dilatation, slight blurring of vision and dryness of mouth, some mental slowing, minimal loss of coordination, no loss of contact with reality, lowest performance score of 60% at 7 h; recovery at approximately 48 h.
1963. Toxicological Studies of Effects of BZ on Animals. S. Army Chemical Research and Development Laboratories, Edgewood Arsenal, MD (as cited in Rosenblatt et al. 1974). NIST (The National Institute of Standards and Technology). 2011. 3-Quinuslidinyl benzilate. NIST Standard Reference Database 69: NIST Chemistry WebBook [online]. ID=6581-06-2&Units=SI [accessed Jan. 9, 2013]. NRC (National Research Council). 1982. Possible Long-Term Health Effects of ShortTerm Exposure to Chemical Agents, Vol.
5. Probit analysis for exposures associated with various TRI indices was reported by Ketchum (1963). The analysis provided an ED50 (a concentrationtime product causing a specific TRI score in 50% of the test subjects) with 95% confidence limits for aerosol exposures (see Table 1-3) for groups of 36 volunteers. S. Department of the Army 1974). Ketchum et al. (1967) also reported the results of field-condition assessments (project DORK) for exposure to BZ aerosols. The assessments appeared to be an extension of the pyrotechnic exposures mentioned above.